The conference has concluded. Registrants have been emailed a link to view the recordings of the conference and the Mini-Talks. If you registered, but did not receive an email with a link to view these videos, please contact

Monday | 24 May 2021

8:00 - 8:15am Introductions and Announcements

8:15 - 9:15am Current Concepts in Gravitational Physiology

Moderator: Marc-Antoine Custaud, MD, PhD and Martina Heer, PhD

“Space anemia, same old or are we making progress?”

Guy Trudel, MD

Professor of Medicine, Surgery and Biochemistry

University of Ottawa, Ottawa, ON, Canada

Bone and Joint Research Laboratory

The Ottawa Hospital Rehabilitation Centre, Ottawa, ON, Canada

MARROW Space Research

International Space Station Payload, Ottawa, ON, Canada

“Self-organized criticality of cardiovascular function in the standing position”

Jacques-Olivier Fortrat, MD, PhD

UMR CNRS 6015 Inserm 1083, Biologie Neurovasculaire et Mitochondriale Intégrée

Laboratoire d'Explorations Fonctionnelles Vasculaires

Centre Hospitalier Universitaire d'Angers, Angers, France

9:15 - 9:20am Break

9:20 - 10:40am Effects of Spaceflight on Physiological Systems

Moderators: Pooneh Bagher, PhD, and Susan Bloomfield, PhD

“Decreasing exhaled nitric oxide before and during prolonged space flight”

D Linnarsson

“Characteristics of locomotion on the passive-mode treadmill at the on ground and space experiments”

E Fomina

“Impact of a four-hour leg cuff session on internal jugular vein distention during spaceflight”

C Patterson

“Effects of microgravity on ocular artery hydrodynamics”

S Tsai

“Middle cerebral jugular and portal vein adaptation to six months ISS spaceflight at rest and with LBNP”

P Arbeille

“Maintenance of central venous pressure and cardiovascular baroreflexes in astronauts tested within hours of return from the International Space Station”

C Mastrandrea

“Space flight cultivation for radish (raphanus sativus) in the advanced plant habitat”

S John

Tuesday | 25 May 2021

8:00 - 9:00am Nutrition and Food

Moderator: Scott Smith, PhD

“Food System Development for Space Exploration: Challenges and Integrative Solutions”

Grace Douglas, PhD

Lead Scientist, Advanced Food Technology

NASA Johnson Space Center, Houston, TX, USA

“Energy Requirements of the Astronauts Onboard the ISS: The ENERGY Protocol”

Audrey Bergouignan, PhD

Institut Plurisdiciplinaire Hubert Curien, Département d'Écologie, Physiology, Éthologie

UMR 7178 - CNRS / Unistra, Université de Strasbourg, Strasbourg, France

9:00 - 9:10am Break

9:10 - 9:20am ISGP Announcements and Updates

9:20 - 10:40am Effects of Spaceflight and Ground-Based Analogs on Bone and Muscle

Moderator: Ruth Globus, PhD

Bone loss due to long-duration spaceflight and the effects of exercise and bone


L Gabel

Characterizing the role of exercise, recovery, and CDKN1a/p21 in mitigating the effect of simulated spaceflight on systemic tissue degeneration

A Kubik

The effect of weightlessness on the skeletal bones of amphibians and reptiles in the context of research on the ultimobranchial gland: results and prospects

V Gulimova

“Pretreatment with anabolic countermeasures enhances cancellous bone in the distal femur of male rats exposed to subsequent unloading”

J Elizondo

21-days of head-down-tilt bed rest result in increased concentrations of cartilage degradation marker CTX-II

AM Liphardt

Foot-ground reaction force during short-radius centrifugation

A Saveko

Progestin-only contraception implants did not exacerbate simulated microgravity induced bone changes

H Allaway

Wednesday | 26 MAy 2021

8:00 - 9:00am Spaceflight Associated Neuro-ocular Syndrome and Cardiovascular

Moderator: Steven Laurie, PhD

“Cerebral and Ocular Results from the SPACE-CENT study: a part of AGBRESA (Artificial Gravity Bed Rest Study)”

Eric Bershad, MD

Associate Professor of Neurology, Neurosurgery and Space Medicine

Section of Neurocritical Care and Vascular Neurology

Baylor College of Medicine, Houston, Texas, USA

“What are the risks to cardiovascular health in human spaceflight?”

Richard Hughson, PhD, FCAHS

Schlegel Research Chair in Vascular Aging and Brain Health

Senior Director of Research

Schlegel-University of Waterloo Research Institute for Aging, Waterloo, ON, Canada

9:00 - 9:10am Break

9:10 - 9:20am ISGP Announcements and Updates

9:20 - 10:40am Cardiovascular Function and Cognition: Examination Using Analog Models

Moderator: Aleksandra Stankovic, PhD

Role of the external carotid artery in maintaining cerebral blood flow in the event of a sudden increase in central blood volume following a change in gravity stress

D Lanéelle

Head down tilt bed rest and arterial stiffness- results from a multi-method approach

S Möstl

“A closed loop approach to the study of the baroreflex dynamics during fast tilt in humans”

A Taboni

Effects of short-term isolation and chronic sleep deprivation on cognitive performance

K Brauns

1-week galvanic vestibular stimulation improves arterial pressure control at the onset of postural change

K Tanaka

Trapped between gravities: The influence of different gravity levels on brain cortical activity

C Badalì

A computational tool for real-time detection of astronaut spatial disorientation during gravitational transitions and piloted landings

J Dixon

Thursday | 27 May 2021

8:00 - 9:00am Effects of Gravity and Spaceflight on Neurovestibular and Sensorimotor Systems

Moderator: Ana Diaz Artiles, PhD

Countermeasures for treating sensorimotor disturbances in astronauts and cosmonauts after long-duration space flights: autonomous landings

Millard Reschke, PhD

Chief, NASA Neuroscience

NASA Johnson Space Center, Houston, TX, USA

“Dry immersion model: overview of unique experiments 2018-2020”

Elena Tomilovskaya, PhD

Senior Researcher,

Head of the Laboratory of Gravitational Physiology of Sensory-motor System,

Head of the Department of Sensory-Motor Physiology and Countermeasures,

Russian Federation State Scientific Center Institute of Biomedical Problems of the Russian Academy of Sciences, Russia, Moscow

9:00 - 9:10am Break

9:10 - 10:30am Modeling Microgravity: Insights from Dry Immersion Studies

Moderators: Marc-Antoine Custaud, PhD and Elena Tomilovskaya, PhD

Changes in response of hemodynamics to head up tilt in healthy people during “dry” immersion and in patients suffering from vasovagal syncope

O Vinogradova

Effect of 21-day support unloading on the characteristics of postural correction responses

N Shishkin

Cardiovascular and fluid changes induced by the acute phase of dry-immersion

A Robin

Microgravity disturbs iron metabolism and hepcidin regulation: lessons from ground-based models in humans and rodents

F Derbré

Effects of thigh-cuffs on bone remodeling unbalance induced by short-term dry immersion and the associated metabolic markers

MT Linossier

Early de-conditioning of human skeletal muscles and effects of a thigh cuff as a cardiovascular countermeasure

T Fovet

“Stimulus-reaction tasks in subjects with Parkinson's disease under repetitive sessions of "dry" immersion: issues of rehabilitation and modeling of interplanetary missions”

A Meigal

10:30 - 10:40am Closing Remarks

MINI-TALKS | On-Demand Presentations

A link will be distributed for all mini-talks no later than 24 May 2021. All mini-talks will be available for viewing to registrants only.

Cardiovascular Function, Psychological Factors, and Cognition: Examination Using Analog Models

Effects of two months of bed rest and antioxidant supplementation on attentional processing

K Brauns

Cognitive performance during 60 days of head-down tilt bedrest with and without artificial gravity (AGBRESA)

L Braunsmann

To study the temporal changes in cardiovascular and cerebrovascular variables during acute exposure to simulated microgravity

S Chauhan

The influence of perceptual constraints on bimanual force coordination in simulated microgravity

M Davis

Analysis of the autonomous nervous system during simulated disorientation test in Italian Air Force pilots

GS Grasso

Sexual Wellbeing & sexual security in Isolation & Confinement Environments (SWICE)

D Grevers

Recent and remote memories are not affected by hypergravity in normotensive and hypertensive rats

A Gros

Assessment of systemic sclerosis patients treated with gravitational therapy

E Isasi

The influence of altered-gravity on bimanual force coordination

D Kennedy

Near-infrared coded hemodynamic imaging tracks changes in venous pressure during head-down tilt and lower body negative pressure

C Patterson

Emotion in space analog environments: detection of affective changes in response to a stressful condition in situation of confinement.

J Pauly

Lower body negative pressure an integrative countermeasure during spaceflight

L Petersen

Improved human performance through control response type for a piloted lunar lander

C Pinedo

Assessment of the relationship between the cardiovascular system during 6-degrees head down tilt using conditional entropy: A terrestrial based microgravity study

V Shankhwar

Cardiovascular effects during parabolic flight: Literature review

H Vellore

Integrated feedback displays to facilitate bimanual coordination in simulated microgravity

Y Wang

Acute gravitational dose-response curves in hemodynamic and ocular variables induced by tilt

R Whittle

Diagnostic Tests and Sensors

Smartphones motion-fingerprint in spaceflight: Motion tracking of astronauts on long duration missions for health monitoring

S Iliev

Space-inspired: E-Nose technology for detection of pneumonia in patients

F Pfeiffer

Effects of Radiation, Simulated Microgravity, or Hypergravity on Physiological Systems

Phosphatase inhibitors have different effects on the motility of fly and mouse spermatozoa under microgravity modeling

M Golubkova

Impact of extreme physical inactivity and low-dose testosterone treatment on iron distribution in male rats

M Horeau

Hypergravity suppresses allergic lung inflammation by attenuating JAK2-STAT3 pathway via Type 2 innate lymphoid cell

YH Kim

Central compensation of x-Irradiation on locomotion: preliminary study for space radiation

G Kim

A review of ambulation energy expenditure in hypogravity analogs

L Kluis

Morphological and functional changes in murine intestine during 30-d hindlimb suspension: a dynamics

E Lagereva

Hypergravity and whole-body vibration affect distinct compartments of mouse bones, with opposite effects in osteopontin or bone sialoprotein knock-outs

M Maalouf

Resolution of inflammation is altered under simulated microgravity conditions

M Maccarrone

Neurobehavioural evaluation of C57BL6 mice exposed to the hindlimb unloading model

A Racca

The Mouse Drawer System (MDS) in the Long Diameter Centrifuge (LDC): neurobehavioral response to altered gravity exposure

D Santucci

Molecular basis of hypergravity-induced wheat root growth phenotype

M Sathasivam

Modeling the effect of curcumin on cancer and healthy breast cells under lunar surface radiation and microgravity conditions

S Sharma

Hypergravity-induced wheat root growth phenotype and associated physio-biochemical parameters

B Swamy

Organization of the cytoskeleton in mouse oocytes under modelling microgravity

M Usik

Effect of centrifuge generated altered-gravity on bimanual coordination

R Woodruff

Effects of Spaceflight and Ground-Based Analogs on Bone and Muscle

Muscle tone - Research in space and ground models. A summary of the results and possible horizons

L Amirova

Tissue-specific sex differences in physiological reactions to simulated microgravity in mice

A Andreev-Andrievskiy

Whole-body reaching movements in micro- and hyper-gravity highlight distinct adaptive processes

L Chomienne

Microgravity-induced effects on motor system: influence of spinal cord stimulation and support afferentation

A Fedianin

Whole-body vibration: an 18-month countermeasure evaluation of postmenopausal women

P Fernandez

Dynamics of functional performance indicators under conditions of a one-year wintering at the Antarctic station “Vostok”

N Osetskiy

Thermoneutral temperature mitigates hind-limb unloading-induced bone loss by preserving energetic metabolism

L Peurière

Denosumab as a potential pharmacological countermeasure against microgravity-induced osteopaenia in long duration space flight – a review and proposal

A Rengel

Role of neuronal control in development of immobilization osteoporosis

D Shcherbakov

Effects of Spaceflight on Physiological Systems

Index of reflectivity of ultrasound radiofrequency signal from the carotid artery wall increases in astronauts after a 6-month spaceflight

P Arbeille

Central and peripheral pulse wave velocity changes in astronauts on ISS and up to one-year post-landing follow-up

D Greaves

Repeated long-term space flights: proteomic investigations of cosmonauts’ blood

D Kashirina

Effect of the exercise countermeasure to prevent the metabolic alterations induced by microgravity: evidence from ground-based and in-flight studies

E Le Roux

Risk factors for the onset of cardiac arrhythmias in astronauts during long-term spaceflights

R Parisi

Lower dampening of carotid artery wave intensity following 6 months on the International Space Station: a Vascular Echo study

A Robertson

Modeling Microgravity: Insights from Dry Immersion Studies

Study of postural stability after 5-day dry immersion with two posturology methods: comparative analysis of video motion capture and inertial motion sensors

N Abu Sheli

Increased the REM sleep stage and blood pressure changes during 21-day dry immersion

E Bersenev

Evaluation of cardiovascular reactions in Parkinson’s disease patients underwent repetitive short-term sessions of “dry” immersion for rehabilitation

L Gerasimova-Meigal

5 days of simulated microgravity promote ectopic adiposity development and ECM remodeling in skeletal muscle

C Guilhot

Prospects for using different classes of otoacoustic emission for intracranial pressure monitoring in astronauts during spaceflight

L Marchenko

Vertebral dysfunctions and viscoelastic properties after 5d Dry Immersion simulating microgravity

C Ple

MRI study of the spinal canal during dry immersion

A Robin

Molecular markers and functional characteristics of human skeletal muscle deconditioning after short-term dry immersion

L Stevens

DI-5-Cuffs. Intervertebral disc content increased after 5-day dry immersion

L Treffel

Parameters of vascular hemodynamics and body fluids redistribution in female volunteers during staying in 3-day “dry” immersion

I Vasilev

Recordings of presentations will be available to registrants after the event. In lieu of poster sessions, 5-minute mini-talks will be available only to registrants as short, pre-recorded video presentations.